Altitude sickness and altitude adaptation

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Acute high-altitude sickness.

At any point 1-5 days following ascent to altitudes ≥2500 m, individuals are at risk of developing one of three forms of acute altitude illness: acute mountain sickness, a syndrome of nonspecific symptoms including headache, lassitude, dizziness and nausea; high-altitude cerebral oedema, a potentially fatal illness characterised by ataxia, decreased consciousness and characteristic changes on m...

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General introduction to altitude adaptation and mountain sickness.

The key elements in acclimatization aim at securing the oxygen supply to tissues and organs of the body with an optimal oxygen tension of the arterial blood. In acute exposure, ventilation and heart rate are elevated with a minimum reduction in stroke volume. In addition, plasma volume is reduced over 24-48 h to improve the oxygen-carrying capacity of the blood, and is further improved during a...

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High Altitude Mountain Sickness

Its probable first account has been given by Plutarch in his comments on Alexander’s invasion of India: “Many then were the dangers— but the greatest harm came from severity of weathers”. Similarly, a Chinese record mentions of “Lesser Headache Mountains” and the “Greater Headache Mountains” where men’s bodies become feverish, they lose color and are attacked with headache, dizziness and vomiti...

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' Adaptation to High Altitude

Hypoxia is inconsequential for physiologically fit persons below an effective altitude of 2640 metres. At higher altitudes, the adaptation is brought about by four main factors, viz., hyperventilation, increased diffusion of oxygen across alveolar membrane, erythrocythemia and maintenance of body hydration. Carbon dioxide sensitivity is markedly elevated at high altitude, both in sojourners and...

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High-altitude headache and acute mountain sickness.

INTRODUCTION Headache is the most common complication associated with exposure to high altitude, and can appear as an isolated high-altitude headache (HAH) or in conjunction with acute mountain sickness (AMS). The purpose of this article is to review several aspects related to diagnosis and treatment of HAH. DEVELOPMENT HAH occurs in 80% of all individuals at altitudes higher than 3000 meters...

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ژورنال

عنوان ژورنال: Acta Physiologica

سال: 2017

ISSN: 1748-1708

DOI: 10.1111/apha.12894